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Table 4 Top five diseases influenced by CHH differential methylation

From: Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis

Disease Molecules related to Disease FDR Molecules
Familial skeletal dysplasia ADAMTS2, DDR2, FAM20C, FDFT1, MYO18B, PDE4D, ROR2, TNFRSF11A 3.06E-07 8
Large intestine adenocarcinoma ADAMTS2, AGT, ATXN3L, BAIAP2L1, CCDC155, CCDC85C, CFAP299, CMIP, CNNM2, CTDP1, DDR2, DNAJB13, FAM20C, FDFT1, FPR3, GAS7, GCM1, GRID2, IL13, IL27, IQCE, ITPK1, KCNJ12, KRT38, MCEE, MYO18B, NAV2, NDUFA10, NPHP4, PCSK6, PDE4D, PGS1, PITPNC1, PLEKHF1, PLEKHM3, PRKCA, PTPRN2, RALGPS2, RASA3, RIMBP2, RIN2, ROR2, RPS19, SLC30A1, SLC6A12, SPATS2L, SPG7, SV2C, TDRD5, TMEM92, TNFRSF11A, ZFYVE28 2.34E-06 52
Hereditary connective tissue disorder ADAMTS2, AGT, CTDP1, DDR2, FAM20C, FDFT1, JDP2, MYO18B, PDE4D, RIN2, ROR2, TNFRSF11A 2.76E-06 12
Abdominal adenocarcinoma ADAMTS2, AGT, ATXN3L, BAIAP2L1, CCDC155, CCDC85C, CFAP299, CMIP, CNNM2, CPNE6, CTDP1, DDR2, DNAJB13, FAM20C, FDFT1, FPR3, GAS7, GCM1, GRID2, IL13, IL27, IQCE, ITPK1, KCNJ12, KRT38, MCEE, MYO18B, NAV2, NDUFA10, NPHP4, PCSK6, PDE4D, PGS1, PITPNC1, PLEKHF1, PLEKHM3, PRKCA, PTPRN2, RALGPS2, RASA3, RIMBP2, RIN2, ROR2, RPS19, SLC30A1, SLC6A12, SPATS2L, SPG7, SSR1, SV2C, TDRD5, TMEM92, TNFRSF11A, ZFYVE28 8.89E-05 54
Liver carcinoma ADAMTS2, AGT, CNNM2, CTDP1, DDR2, DNAJB13, FAM20C, FPR3, GAS7, GRID2, IL27, IQCE, JDP2, KCNJ12, MYO18B, NAV2, NDUFA10, NPHP4, PDE4D, PGS1, PITPNC1, PTPRN2, RALGPS2, RASA3, RIMBP2, RIN2, SLC30A1, SLC6A12, TDRD5, TNFRSF11A, ZFYVE28 2.32E-04 31