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Fig. 7 | BMC Medical Genomics

Fig. 7

From: High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome

Fig. 7

Changes in the amounts of available miRNA binding sites present on circRNAs do not correlate with changes in miRNA expression levels in lesional- relative to non-lesional skin. (a-b) For each miRNA, the sum of the number of binding sites for that particular miRNA was multiplied with the mean circRNA RPM (lesional) - mean circRNA RPM (non-lesional) for the circRNAs harboring binding sites for that particular miRNA. These values were plotted against either the fold change (mean miRNA counts (lesional)/mean miRNA counts (non-lesional)) for each high abundance miRNA with at least one binding site present on the high abundance circRNAs (a) or the absolute difference in expression level (mean miRNA counts (lesional) - mean miRNA counts (non-lesional)) for each high abundance miRNA with at least one binding site present on the high abundance circRNAs (b)

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BMC Medical Genomics

ISSN: 1755-8794

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