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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Systematic computational identification of prognostic cytogenetic markers in neuroblastoma

Fig. 4

Fifty-eight robust chromosome bands were associated with patient survival. a An overview of the 272 chromosome bands with frequency of gain/loss events and prognosis. Track a shows a histogram of the gain/loss frequency in the Pugh dataset. Track b shows a histogram of the gain/loss frequency in the Kocak dataset. Track c shows the gain/loss status for each chromosome band. Dark purple represents frequent gain. Light purple represents frequent loss. Gray represents nonfrequent gain/loss. Track d shows the association between chromosome aberration and prognosis in the Su dataset. Green presents the high frequency of gain/loss chromosome bands associated with prognosis. Gray presents non-association with prognosis. Track e shows the association between chromosome aberration and prognosis in the Oberthuer dataset. Red presents chromosome bands with high gain/loss frequency associated with prognosis. Gray presents non-association with prognosis. b The overlapping prognostic-associated chromosome bands in the Su and Oberthuer dataset. c The number of frequent gain/loss chromosome bands associated with good/bad outcome. d Detailed information on the 58 robust chromosome bands associated with patient survival

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