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Table 5 Ten top-ranked pathways in GBM by Cox-PASNet

From: Interpretable deep neural network for cancer survival analysis by integrating genomic and clinical data

Pathway nameSizeP-valueRef.
Jak-STAT signaling pathway155<0.0001[3537]
Neuroactive ligand-receptor interaction272<0.0001[38]
MAP kinase activation in TLR cascade500.0176
NF κB and MAP kinases activation mediated by TLR4 signaling repertoire720.0729
G alpha (i) signalling events195<0.0001
PI3K cascade710.0304[39, 40]
Tyrosine metabolism420.5671
Neuronal system279<0.0001[41]
Axon guidance1290.0012[37]
Xenobiotics160.6347