Interpretable deep neural network for cancer survival analysis by integrating genomic and clinical data

BMC Medical Genomics

Table 5 Ten top-ranked pathways in GBM by Cox-PASNet

Pathway name	Size	P-value	Ref.
Jak-STAT signaling pathway	155	<0.0001	[35–37]
Neuroactive ligand-receptor interaction	272	<0.0001	[38]
MAP kinase activation in TLR cascade	50	0.0176	–
NF κB and MAP kinases activation mediated by TLR4 signaling repertoire	72	0.0729	–
G alpha (i) signalling events	195	<0.0001	–
PI3K cascade	71	0.0304	[39, 40]
Tyrosine metabolism	42	0.5671	–
Neuronal system	279	<0.0001	[41]
Axon guidance	129	0.0012	[37]
Xenobiotics	16	0.6347	–

ISSN: 1755-8794