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Table 3 Best performing DNN architectures.

From: A deep neural network approach to predicting clinical outcomes of neuroblastoma patients

Configuration

Architecture

Balanced accuracy

Clinical outcome = ‘Death from disease

Fischer-M, centralities

[8,8,8,2]

87.3%

Fischer-M, modularities

[8,4]

83.9%

Fischer-M, both

[8,8,8]

86.8%

Fischer-R, centralities

[8,8,8,4]

85.8%

Fischer-R, modularities

[8,8,8,2]

82.1%

Fischer-R, both

[2,2,2,2]

85.2%

Fischera, centralities

[8,2,2]

86.1%

Fischera, modularities

[8,2,2]

84.7%

Fischera, both

[8,8,4]

84.7%

Clinical outcome = ‘Disease progression

Fischer-M, centralities

[8,8,8,2]

84.3%

Fischer-M, modularities

[8,8,2]

82.3%

Fischer-M, both

[4,4,2]

83.7%

Fischer-R, centralities

[8,8,4]

83.7%

Fischer-R, modularities

[8,2,2]

79.1%

Fischer-R, both

[8,8,8,8]

77.9%

Fischera, centralities

[4,2,2,2]

84.7%

Fischera, modularities

[8,8]

79.6%

Fischera, both

[4,2]

81.5%

  1. One row corresponds to the best model for a given clinical outcome and configuration (from Table 2). The best performance (i.e., balanced accuracy) is displayed in bold for each clinical outcome
  2. aCombined dataset in which the topological features of both ‘Fischer-M’ and ‘Fischer-R’ are concatenated