Fig. 4
From: Finding prognostic gene pairs for cancer from patient-specific gene networks
Comparison of the prognostic power of gene pairs and single genes in BRCA. a The survival rates of two groups of BRCA samples with respect to prognostic gene pairs LINC01234_MET and KRT5_SP1. b The survival rates of two groups of BRCA samples with respect to four single genes (LINC01234, MET, KRT5 and SP1) involved in the gene pairs of a. c The survival rates of two groups of BRCA samples with respect to two genes (CASP9 and FGF14-AS2) which showed the lowest adjusted p-value in the log-rank test. None of the 6 single genes (LINC01234, MET, KRT5, SP1, CASP9 and FGF14-AS2) are predictive of survival rates. Group 1: cancer samples with the top 25% ΔPCC of the corresponding gene pair from the normal samples. Group 2: the remaining cancer samples of the same cancer type. High expression: cancer samples with higher expression levels than the average expression level. Low expression: remaining cancer samples