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Table 4 Functional enrichment analysis of the genes in the prognostic gene pairs for breast cancer

From: Finding prognostic gene pairs for cancer from patient-specific gene networks

  #genesp-valueFDR
Annotation cluster 1Enrichment score: 13.55   
KEGG_PATHWAYhsa05200:Pathways in cancer361.64E-221.98E-19
KEGG_PATHWAYhsa05215:Prostate cancer151.40E-121.70E-09
KEGG_PATHWAYhsa04151:PI3K-Akt signaling pathway199.74E-081.18E-04
Annotation cluster 2Enrichment score: 7.93   
KEGG_PATHWAYhsa04510:Focal adhesion182.31E-102.80E-07
KEGG_PATHWAYhsa05205:Proteoglycans in cancer161.13E-081.37E-05
KEGG_PATHWAYhsa04015:Rap1 signaling pathway162.20E-082.66E-05
KEGG_PATHWAYhsa05100:Bacterial invasion of epithelial cells103.23E-073.91E-04
Annotation cluster 3Enrichment score: 6.62   
UP_KEYWORDSGrowth factor117.37E-099.42E-06
GOTERM_MF_DIRECTGO:0008083 growth factor activity122.54E-083.52E-05
GOTERM_BP_DIRECTGO:0050679 positive regulation of epithelial cell proliferation67.40E-051.25E-01
Annotation cluster 4Enrichment score: 5.44   
GOTERM_MF_DIRECTGO:0044212 transcription regulatory region DNA binding134.59E-086.36E-05
GOTERM_BP_DIRECTGO:0045893 positive regulation of transcription, DNA-templated179.99E-071.69E-03
GOTERM_BP_DIRECTGO:0045892 negative regulation of transcription, DNA-templated121.03E-031.73E-00