Table 4 The number of pathogenic mutations identified in 253 unpaired tumour samples in five genes that are frequently mutated in ovarian cancer. The number of unique mutations is shown and in brackets the number of samples with at least one mutation is shown
From: Comparison of somatic variant detection algorithms using Ion Torrent targeted deep sequencing data
| Â | BRCA1 | BRCA2 | KRAS | PIK3CA | TP53 |
|---|---|---|---|---|---|
MuTect2 | 1190 (n = 243) | 390 (n = 248) | 56 (n = 202) | 47 (n = 186) | 820 (n = 246) |
TVC | 164 (n = 89) | 54 (n = 42) | 11 (n = 34) | 18 (n = 27) | 215 (n = 175) |
Common | 163 (n = 85) | 52 (n = 42) | 11 (n = 34) | 14 (n = 24) | 210 (n = 173) |
Common (%) | 13.7% (34.4%) | 13.3% (16.9%) | 19.6% (16.8%) | 27.5% (12.7%) | 25.5% (69.8%) |