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Table 2 MiR-182-5p expression in NSCLC data from RT-qPCR

From: MiR-182-5p and its target HOXA9 in non-small cell lung cancer: a clinical and in-silico exploration with the combination of RT-qPCR, miRNA-seq and miRNA-chip

Clinicopathological parameters n Relevant expression of miR-182-5p (2−ΔCq)
Mean ± SD t/F-value p-value
Tissue NSCLC 124 29.615 ± 5.616 13.979 < 0.001*
Noncancerous 124 22.859 ± 3.669
Gender Male 74 30.144 ± 5.497 1.278 0.204
Female 50 28.833 ± 5.755
Age (years) < 60 56 30.913 ± 5.052 2.413 0.017*
≥60 68 28.547 ± 5.864
Smoke No 38 31.184 ± 5.185 0.720 0.474
Yes 29 30.237 ± 5.530
Histological type Adenocarcinoma 101 29.337 ± 5.717 −1.245 0.221
Squamous carcinoma 23 30.836 ± 5.086
Tumor size ≤3 cm 60 24.995 ± 4.570 −14.353 < 0.001*
> 3 cm 64 33.947 ± 1.620
Vascular invasion No 90 29.456 ± 5.720 −0.512 0.609
Yes 34 30.037 ± 5.391
TNM I-II 54 27.131 ± 5.424 −4.632 < 0.001*
III-IV 70 31.532 ± 5.007
Lymph node metastasis No 56 26.621 ± 5.128 −6.095 < 0.001*
Yes 68 32.081 ± 4.759
Pathological grading I 17 27.642 ± 5.863 1.246a 0.291
II 77 29.853 ± 5.721
III 30 30.124 ± 5.131
  1. NSCLC: non-small cell lung cancer; SD: standard deviation
  2. a One-way analysis of variance (ANOVA) was performed
  3. * The results were statistically significant (P < 0.05)