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Table 4 MiR-182-5p expression in NSCLC from miRNA-seq data

From: MiR-182-5p and its target HOXA9 in non-small cell lung cancer: a clinical and in-silico exploration with the combination of RT-qPCR, miRNA-seq and miRNA-chip

Clinicopathological featurenRelevant expression of miR-182-5p (log2x)
Mean ± SDt/F-valueP-value
TissueLung cancer78414.332 ± 1.04221.214< 0.001*
Noncancerous8911.962 ± 0.994
Histological typeAdenocarcinoma44814.273 ± 0.947−1.7850.075
Squamous carcinoma33614.411 ± 1.154
GenderMale46014.367 ± 1.0421.1370.256
Female32414.282 ± 1.042
Age(years)≤6021314.396 ± 1.0401.1690.243
> 6054614.297 ± 1.055
TT1 + T265414.358 ± 1.0381.2420.214
T3 + T412714.232 ± 1.051
NodesNo50914.315 ± 1.050−1.1820.238
Yes26014.408 ± 1.006
MetastasisNo54014.376 ± 1.0410.3280.743
Yes2114.302 ± 1.029
Pathologic stageI-II63114.320 ± 1.063−0.4810.631
III-IV14514.366 ± 0.962
Anatomic organ subdivisionL-Lower11214.285 ± 1.0290.662a0.618
L-Upper19814.240 ± 0.995
R-Lower16014.390 ± 1.073
R-Middle2914.416 ± 1.008
R-Uppr24914.359 ± 1.026
Tumor locationPeripheral18714.342 ± 1.013−0.2100.834
Central16214.366 ± 1.130
  1. NSCLC: non-small cell lung cancer; SD: standard deviation
  2. a One-way analysis of variance (ANOVA) was performed
  3. * The results were statistically significant (P < 0.05)