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Table 4 MiR-182-5p expression in NSCLC from miRNA-seq data

From: MiR-182-5p and its target HOXA9 in non-small cell lung cancer: a clinical and in-silico exploration with the combination of RT-qPCR, miRNA-seq and miRNA-chip

Clinicopathological feature n Relevant expression of miR-182-5p (log2x)
Mean ± SD t/F-value P-value
Tissue Lung cancer 784 14.332 ± 1.042 21.214 < 0.001*
Noncancerous 89 11.962 ± 0.994
Histological type Adenocarcinoma 448 14.273 ± 0.947 −1.785 0.075
Squamous carcinoma 336 14.411 ± 1.154
Gender Male 460 14.367 ± 1.042 1.137 0.256
Female 324 14.282 ± 1.042
Age(years) ≤60 213 14.396 ± 1.040 1.169 0.243
> 60 546 14.297 ± 1.055
T T1 + T2 654 14.358 ± 1.038 1.242 0.214
T3 + T4 127 14.232 ± 1.051
Nodes No 509 14.315 ± 1.050 −1.182 0.238
Yes 260 14.408 ± 1.006
Metastasis No 540 14.376 ± 1.041 0.328 0.743
Yes 21 14.302 ± 1.029
Pathologic stage I-II 631 14.320 ± 1.063 −0.481 0.631
III-IV 145 14.366 ± 0.962
Anatomic organ subdivision L-Lower 112 14.285 ± 1.029 0.662a 0.618
L-Upper 198 14.240 ± 0.995
R-Lower 160 14.390 ± 1.073
R-Middle 29 14.416 ± 1.008
R-Uppr 249 14.359 ± 1.026
Tumor location Peripheral 187 14.342 ± 1.013 −0.210 0.834
Central 162 14.366 ± 1.130
  1. NSCLC: non-small cell lung cancer; SD: standard deviation
  2. a One-way analysis of variance (ANOVA) was performed
  3. * The results were statistically significant (P < 0.05)