MiR-182-5p and its target HOXA9 in non-small cell lung cancer: a clinical and in-silico exploration with the combination of RT-qPCR, miRNA-seq and miRNA-chip

Li Gao; Shi-bai Yan; Jie Yang; Jin-liang Kong; Ke Shi; Fu-chao Ma; Lin-zhen Huang; Jie Luo; Shu-ya Yin; Rong-quan He; Xiao-hua Hu; Gang Chen

doi:10.1186/s12920-019-0648-7

Table 5 Characteristics of included GEO miRNA-chips

From: MiR-182-5p and its target HOXA9 in non-small cell lung cancer: a clinical and in-silico exploration with the combination of RT-qPCR, miRNA-seq and miRNA-chip

	First author	Experiment type	Sample type	Platform	Cancer (N)	Cancer (M)	Cancer (SD)	Noncancer (N)	Noncancer (M)	Noncancer (SD)	TP	FP	FN	TN
GSE14936	Seike M	Non-coding RNA profiling by array	tissue	GPL8879	10	7.763	0.850	9	8.137	0.819	8	7	2	2
GSE15008	Tan X	Non-coding RNA profiling by array	tissue	GPL2009	187	11.401	1.255	188	9.697	0.867	44	1	143	187
GSE16512	Lodes MJ	Non-coding RNA profiling by array	serum	GPL8686	3	−0.024	0.031	14	−0.338	0.23	1	1	2	13
GSE17681	Keller A	miRNA Profiling	serum	GPL9040	17	12.652	0.756	19	12.174	0.753	7	1	10	18
GSE18692A	Puisségur MP	Non-coding RNA profiling by array	tissue	GPL4717	7	0.458	0.304	7	0.251	0.153	5	1	2	6
GSE18692B	Puisségur MP	Non-coding RNA profiling by array	tissue	GPL4718	13	0.288	0.343	13	0.403	0.34	10	11	3	2
GSE19945	Ohba T	Non-coding RNA profiling by array	tissue	GPL9948	20	−0.325	1.781	8	−2.799	0.554	15	0	5	8
GSE24709	Andreas Keller	Non-coding RNA profiling by array	serum	GPL9040	28	12.253	0.532	19	11.626	0.775	17	0	11	19
GSE27486	Santosh Kumar Patnaik	Non-coding RNA profiling by array	serum	GPL11432	22	5.680	0.428	23	5.731	0.646	11	10	12	13
GSE27705	Chris Fenton	Non-coding RNA profiling by array	tissue	GPL11432	20	0.106	0.934	10	−1.187	0.196	19	1	1	9
GSE29248	lina ma	Non-coding RNA profiling by array	tissue	GPL8179	6	12.643	0.704	6	11.099	2.171	3	0	3	6
GSE31568	Andreas Keller	Non-coding RNA profiling by array	serum	GPL9040	32	12.173	0.607	70	11.847	0.972	12	5	20	65
GSE33045	Sonia Molina-Pinelo	Expression profiling by RT-PCR	serum	GPL13987	12	12.618	1.642	8	13.291	1.223	12	7	0	1
GSE36681	Jin Sung Jang	Non-coding RNA profiling by array	tissue	GPL8179	103	12.151	1.215	103	11.282	1.232	16	1	87	102
GSE40738	Santosh Kumar Patnaik	Non-coding RNA profiling by array	serum	GPL16016	81	5.225	0.581	56	5.025	0.675	8	1	73	55
GSE46729	Zongli Xu	Non-coding RNA profiling by array	serum	GPL8786	24	4.530	0.227	24	4.423	0.215	5	1	19	23
GSE47525	Maikel Wouters	Non-coding RNA profiling by array	tissue	GPL17222	18	4.927	0.716	14	4.727	0.412	7	1	11	13
GSE48414	Maria Moksnes Bjaanæs	Non-coding RNA profiling by array	tissue	GPL16770	154	−0.364	2.547	20	−3.548	2.166	120	0	34	20
GSE51853	Takashi Takahashi	Non-coding RNA profiling by array	tissue	GPL7341	124	1.177	1.045	5	−1.459	0.381	120	0	4	5
GSE53882	Heng-Ying Pu	Expression profiling by array	tissue	GPL18130	397	1.245	0.446	151	1.172	0.428	11	1	386	150
GSE56036	Satoshi Kondo	Non-coding RNA profiling by array	tissue	GPL15446	28	6.397	1.319	27	4.166	0.663	25	1	3	26
GSE61741	Andreas Keller	Non-coding RNA profiling by array	serum	GPL9040	72	12.342	0.656	94	12.302	0.514	26	25	46	69
GSE68951	Christina Backes	Non-coding RNA profiling by array	serum	GPL16770	203	1.225	0.336	12	1.149	0.144	92	1	111	11
GSE74190	Lu Shaohua	Non-coding RNA profiling by array	tissue	GPL19622	66	0.761	1.650	44	−3.404	2.568	36	1	30	43
GSE93300	qu lili	Non-coding RNA profiling by array	tissue	GPL21576	9	−6.044	0.938	4	−8.187	0.885	8	0	1	4

Note: N: number; M: median; SD: standard deviation; TP: true positivity; FP: false positivity; FN: false negativity; TN: true negativity

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