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Table 6 Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of candidate target genes of miR-182-5p

From: MiR-182-5p and its target HOXA9 in non-small cell lung cancer: a clinical and in-silico exploration with the combination of RT-qPCR, miRNA-seq and miRNA-chip

CategoryItemCountP-value
GO-BPaxonogenesis46< 0.001
GO-BPaxon development48< 0.001
GO-BPRas protein signal transduction45< 0.001
GO-BPeye development37< 0.001
GO-BPmesenchyme development30< 0.001
GO-CCcell leading edge37< 0.001
GO-CCactin cytoskeleton400.002
GO-CCcortical cytoskeleton150.002
GO-CClamellipodium210.002
GO-CCcell cortex280.002
GO-MFtranscription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding41< 0.001
GO-MFtranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding38< 0.001
GO-MFtranscriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding28< 0.001
GO-MFproximal promoter sequence-specific DNA binding37< 0.001
GO-MFnucleoside-triphosphatase regulator activity31< 0.001
KEGGAxon guidance21< 0.001
KEGGMelanogenesis15< 0.001
KEGGLongevity regulating pathway - multiple species11< 0.001
KEGGParathyroid hormone synthesis, secretion and action14< 0.001
KEGGGlutamatergic synapse14< 0.001
  1. Note: BP: biological process; CC: cellular component; MF: molecular function