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Fig. 3 | BMC Medical Genomics

Fig. 3

From: MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis

Fig. 3

The effect of miR-361-5p on MEG3 in OA chondrocytes. a, qRT-PCR detection of miR-361-5p expression. b, cell proliferation detected by CCK-8 assay. c, detection of PCNA, Ki67 expression by western blot. d, flow cytometry was used to detect the apoptosis of OA chondrocytes in each group. e, the expression of apoptotic proteins Bcl-2 and Bax detected by Western Blot. f, Western blot analysis of cartilage matrix protein expression in chondrocytes of each group. *, P < 0.05 compared with Blank group or NC + mimics NC group. #, P < 0.05 compared with MEG3 + mimics NC group

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