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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Effects of ordered mutations on dynamics in signaling networks

Fig. 4

Analysis of ordered-mutation-inducing dynamics with respect to drug-targets in signaling networks. (a-c) Mutation-sensitivity results in HCS, KEGG, and TGL, respectively. All genes were specified by ‘Drug-target (DT)’ and ‘Non-drug-target (Non-DT)’, and every gene pair was classified into four groups, ‘DT → DT’, ‘DT → Non-DT’, ‘Non-DT → DT’, and ‘Non-DT → Non-DT’. (d-f) Order-specificity results in HCS, KEGG, and TGL, respectively. Time gap (T) was set to 2–20 in HCS and KEGG networks, and 1–10 in TGL networks. The error bar represents the standard error deviation

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