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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Effects of ordered mutations on dynamics in signaling networks

Fig. 5

Comparison of ordered-mutation-inducing dynamics between gene pairs targeting same and different drugs in signaling networks. All pairs of genes were classified into ‘Same-drug’ or ‘Different-drug’ groups if the two genes in a pair target a same drug or different drugs, respectively. (a-b) Mutation-sensitivity results in HCS and KEGG, respectively. (c-d) Order-specificity results in HCS and KEGG, respectively. All time gap (T) was set to 2–20. The error bar represents the standard error deviation. Note that TGL network was excluded from analysis, because there was no pair of genes belonging to ‘Same-drug’ group

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