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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Genome-wide analysis reveals the association between alternative splicing and DNA methylation across human solid tumors

Fig. 3

Differentially methylated CpGs at alternatively spliced exon boundaries in multiple tumors. a Volcano plot showing a comparison of the methylation level of CpGs for tumor tissues versus adjacent normal tissues. This plot depicts the biological significance (|meth|) ≥ 10%) on the X axis and the statistical significance (−log10 FDR) on the Y axis. b The proportion of hypomethylated and hypermethylated CpGs at cancer-specific alternative spliced exon boundaries in different tumors. c The proportion of hypomethylated and hypermethylated CpGs at cancer-specific alternative spliced exon boundaries in different splicing types

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