Tumor type | Gene expression | PSI | Methylation level | ||||||
---|---|---|---|---|---|---|---|---|---|
Gene | P | HR(95%CI) | Alternative Exon | P | HR(95%CI) | CpGs | P | HR(95%CI) | |
BRAC | FAXDC2 | 0.558 | 0.96 (0.84,1.10) | 3 | 0.036 | 3.98 (1.09,0.04) | cg18260397 | 0.428 | 0.57 (0.14,2.31) |
COAD | OBSCN | 0.753 | 0.97 (0.78,1.20) | 118 | 0.001 | 0.20 (0.20,0.08) | cg25318301 | 0.380 | 0.48 (0.09,2.49) |
 |  |  |  |  |  |  | cg03669282 | 0.581 | 0.72 (0.23,2.31) |
HNSC | ABL2 | 0.489 | 1.10 (0.84,1.42) | 2 | 0.020 | 4.59 (1.27,16.58) | cg03471346 | 0.095 | 0.40 (0.14,1.17) |
HNSC | DNASE1L1 | 0.003 | 1.45 (1.13,1.86) | 3.1 | 0.007 | 4.40 (1.49,12.95) | cg21459545 | 0.788 | 0.84 (0.25,2.90) |
HNSC | RARA | 0.393 | 1.16 (0.82,1.63) | 5 | 0.009 | 0.08 (0.01,0.54) | cg05824218 | 0.350 | 1.93 (0.49,7.64) |
KIRC | ATG16L2 | 0.104 | 1.14 (0.97,0.10) | 4.1:4.2 | 0.011 | 6.79 (1.55,29.83) | cg21806242 | 0.187 | 13.92 (0.28,698.07) |
KIRC | EGFLAM | 0.957 | 1.00 (0.85,1.17) | 20.1 | 0.047 | 0.43 (0.18,0.99) | cg21201393 | 0.197 | 4.73 (0.45,50.22) |
KIRC | EVL | 0.004 | 1.47 (1.13,1.90) | 3 | 0.027 | 0.32 (0.12,0.88) | cg18621299 | 0.885 | 0.84 (0.07,9.47) |
KIRC | FMNL1 | 0.318 | 1.13 (0.89,1.42) | 13.1 | 0.010 | 3.59 (1.37,9.44) | cg19735250 | 0.261 | 2.95 (0.45,19.42) |
KIRC | NAV2 | 0.276 | 1.17 (0.88,1.54) | 17 | 0.014 | 96.94 (2.48,3787.07) | cg19222784 | 0.857 | 0.82 (0.10,6.76) |
 |  |  |  |  |  |  | cg20949700 | 0.997 | 1.00 (0.13,7.54) |
KIRC | SIGIRR | 0.668 | 1.06 (0.80,1.40) | 2 | 0.041 | 6.29 (1.08,36.63) | cg02585906 | 0.173 | 0.24 (0.03,1.88) |
 |  |  |  |  |  |  | cg23029021 | 0.005 | 0.08 (0.01,0.47) |
KIRC | TBC1D14 | 0.908 | 0.98 (0.65,1.46) | 4 | 0.024 | 26.17 (1.52,449.63) | cg16851482 | 0.778 | 1.44 (0.12,17.83) |
KIRC | ZNF577 | 0.975 | 1.00 (0.82,1.22) | 1.2:1.3 | 0.009 | 6.05 (1.57,23.33) | cg03562414 | 0.471 | 1.59 (0.45,5.62) |
 |  |  |  |  |  |  | cg10635122 | 0.320 | 2.03 (0.50,8.22) |
 |  |  |  |  |  |  | cg11269599 | 0.007 | 7.39 (1.74,31.47) |
 |  |  |  |  |  |  | cg10783469 | 0.214 | 2.73 (0.56,13.32) |
 |  |  |  |  |  |  | cg16731240 | 0.030 | 4.41 (1.16,16.78) |
 |  |  |  |  |  |  | cg23010048 | 0.053 | 4.04 (0.98,16.61) |
 |  |  |  |  |  |  | cg24794228 | 0.228 | 2.28 (0.60,8.69) |
KIRP | C19orf25 | 0.012 | 0.50 (0.29,0.86) | 2.4 | 0.006 | 0.01 (0.00,0.26) | cg16613938 | 0.665 | 0.55 (0.04,8.14) |
 |  |  |  |  |  |  | cg23291200 | 0.980 | 0.94 (0.01,163.12) |
KIRP | CABP1 | 0.0004 | 0.72 (0.60,0.87) | 3.1 | 0.004 | 59.40 (3.63,972.14) | cg24292016 | 0.011 | 0.02 (0.00,0.42) |
 |  |  |  |  |  |  | cg25969992 | 0.011 | 0.04 (0.00,0.49) |
KIRP | CALD1 | 0.632 | 0.88 (0.52,1.49) | 2 | 0.013 | 8.85 (1.58,49.62) | cg04874031 | 0.007 | 149.57 (3.97,5636.65) |
 |  |  |  |  |  |  | cg16253634 | 0.019 | 148.62 (2.24,9849.90) |
 |  |  |  |  |  |  | cg24956866 | 0.027 | 97.96 (1.70,5637.50) |
KIRP | CALD1 | 0.632 | 0.88 (0.52,1.49) | 5 | 0.013 | 0.11 (0.02,0.63) | cg04874031 | 0.007 | 149.57 (3.97,5636.65) |
 |  |  |  |  |  |  | cg16253634 | 0.019 | 148.62 (2.24,9849.90) |
 |  |  |  |  |  |  | cg24956866 | 0.027 | 97.96 (1.70,5637.50) |
KIRP | CCL28 | 0.918 | 1.01 (0.82,1.25) | 2 | 0.009 | 7.17 (1.64,31.37) | cg04187185 | 0.365 | 0.50 (0.11,2.26) |
 |  |  |  |  |  |  | cg16324633 | 0.027 | 10.72 (1.31,87.54) |
KIRP | CIRBP | 0.004 | 0.38 (0.20,0.73) | 8.2:8.3 | 0.011 | 82.29 (2.75,2460.57) | cg02644867 | 0.480 | 3.51 (0.11,113.99) |
KIRP | DNASE1L1 | 0.118 | 2.15 (0.82,5.63) | 3.1 | 0.030 | 29.90 (1.40,637.29) | cg21459545 | 0.251 | 0.32 (0.05,2.24) |
 |  |  |  |  |  |  | cg22562219 | 0.081 | 0.08 (0.01,1.36) |
 |  |  |  |  |  |  | cg24834461 | 0.224 | 0.20 (0.02,2.63) |
KIRP | PIGQ | 0.703 | 0.88 (0.46,1.68) | 3 | 0.047 | 0.05 (0.00,0.96) | cg03815552 | 0.575 | 0.23 (0.00,38.74) |
KIRP | SLC9A3R2 | 0.650 | 1.11 (0.70,1.78) | 3 | 0.020 | 0.05 (0.00,0.62) | cg08601673 | 0.263 | 0.16 (0.01,3.97) |
KIRP | TM4SF18 | 0.001 | 0.58 (0.41,0.81) | 2.1 | 0.015 | 0.04 (0.00,0.55) | cg11011913 | 0.087 | 4.98 (0.79,31.30) |
LIHC | C1QTNF1 | 0.580 | 1.03 (0.93,1.13) | 5 | 0.008 | 0.27 (0.10,0.70) | cg23882796 | 0.553 | 1.24 (0.61,2.51) |
LUAD | GALK2 | 0.013 | 1.58 (1.10,2.26) | 3.1 | 0.002 | 13.29 (2.53,69.98) | cg08036668 | 0.219 | 0.42 (0.11,1.67) |
LUSC | AHCYL2 | 0.158 | 1.14 (0.95,1.36) | 3 | 0.031 | 1.88 (1.06,3.33) | cg15664152 | 0.933 | 1.03 (0.51,2.06) |
LUSC | AQP1 | 0.022 | 1.13 (1.02,1.26) | 7.1 | 0.046 | 3.51 (1.02,12.06) | cg07135629 | 0.952 | 1.04 (0.32,3.41) |
 |  |  |  |  |  |  | cg04551925 | 0.790 | 0.86 (0.28,2.65) |
 |  |  |  |  |  |  | cg10132917 | 0.645 | 1.29 (0.44,3.82) |
 |  |  |  |  |  |  | cg11827925 | 0.141 | 1.95 (0.80,4.73) |
 |  |  |  |  |  |  | cg04372674 | 0.049 | 2.22 (1.00,4.89) |
 |  |  |  |  |  |  | cg25075794 | 0.047 | 2.20 (1.01,4.79) |
 |  |  |  |  |  |  | cg25230363 | 0.038 | 2.42 (1.05,5.57) |
LUSC | AQP1 | 0.022 | 1.13 (1.02,1.26) | 7.1 | 0.046 | 3.51 (1.02,12.06) | cg26923410 | 0.052 | 2.42 (0.99,5.90) |
 |  |  |  |  |  |  | cg15373767 | 0.122 | 2.07 (0.82,5.21) |
 |  |  |  |  |  |  | cg18080604 | 0.049 | 2.74 (1.00,7.50) |
 |  |  |  |  |  |  | cg09676669 | 0.078 | 2.31 (0.91,5.84) |
LUSC | ARHGAP24 | 0.279 | 0.92 (0.80,1.07) | 6 | 0.042 | 145.84 (1.20,17,748.46) | cg14376467 | 0.908 | 1.04 (0.52,2.09) |
 |  |  |  |  |  |  | cg13889934 | 0.997 | 1.00 (0.48,2.11) |
 |  |  |  |  |  |  | cg21446955 | 0.892 | 1.05 (0.49,2.24) |
LUSC | ERG | 0.738 | 1.03 (0.86,1.24) | 5 | 0.038 | 2.25 (1.05,4.86) | cg01613817 | 0.581 | 0.78 (0.32,1.91) |
LUSC | FAXDC2 | 0.285 | 1.07 (0.94,1.22) | 5.1 | 0.047 | 2.09 (1.01,4.31) | cg02379533 | 0.624 | 0.76 (0.25,2.28) |
LUSC | GCNT2 | 0.970 | 1.00 (0.89,1.12) | 6.1 | 0.012 | 2.21 (1.19,4.11) | cg13411789 | 0.146 | 0.66 (0.37,1.16) |
LUSC | IL1RN | 0.721 | 0.98 (0.89,1.08) | 3 | 0.046 | 0.55 (0.31,0.99) | cg11783497 | 0.833 | 1.11 (0.42,2.89) |
LUSC | NAV1 | 0.569 | 0.96 (0.85,1.09) | 6 | 0.024 | 0.49 (0.26,0.91) | cg01411786 | 0.765 | 1.16 (0.44,3.03) |
 |  |  |  |  |  |  | cg05091570 | 0.982 | 0.99 (0.39,2.50) |
 |  |  |  |  |  |  | cg13877974 | 0.356 | 0.55 (0.15,1.97) |
 |  |  |  |  |  |  | cg16023122 | 0.334 | 0.48 (0.11,2.13) |
 |  |  |  |  |  |  | cg01828733 | 0.350 | 0.59 (0.19,1.79) |
LUSC | PLEC | 0.133 | 1.13 (0.96,1.32) | 4 | 0.006 | 23.29 (2.50,216.60) | cg00329447 | 0.117 | 0.53 (0.24,1.17) |
 |  |  |  |  |  |  | cg06452769 | 0.033 | 0.41 (0.18,0.93) |
PRAD | EXOC7 | 0.346 | 0.61 (0.22,1.70) | 8.2 | 0.038 | 40.29 (1.22,1329.36) | cg04470878 | 0.660 | 4.86 (0.00,5523.54) |
PRAD | FHAD1 | 0.358 | 1.14 (0.86,1.53) | 15.2 | 0.041 | 0.26 (0.07,0.95) | cg07312051 | 0.675 | 5.04 (0.00,9748.17) |
PRAD | PCDHA9 | 0.592 | 0.94 (0.75,1.17) | 1.2 | 0.007 | 14.70 (2.12,102.01) | cg18029321 | 0.548 | 28.37 (0.00,1,537,765.42) |
THCA | EGFLAM | 0.828 | 1.06 (0.65,1.73) | 20.1 | 0.028 | 0.10 (0.01,0.78) | cg21201393 | 0.705 | 1.97 (0.60,64.65) |