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Fig. 3 | BMC Medical Genomics

Fig. 3

From: MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

Fig. 3

Distribution of absolute copy numbers. Copy numbers were called with ReadDepth of cancer cell line HCC2218 after segmentation (6,867,679 segments with an average segment length of 450 bp). a The bias occurs around each integer copy number and is lower for CNRD ~ 1, but increases for CNRD ~ 2. The factor for normalisation is a linear function (eq. 1b) which serves to adjust the bias for different CNRD. b Distribution of absolute copy numbers called with ReadDepth after normalisation

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