Fig. 3From: MetaCNV - a consensus approach to infer accurate copy numbers from low coverage dataDistribution of absolute copy numbers. Copy numbers were called with ReadDepth of cancer cell line HCC2218 after segmentation (6,867,679 segments with an average segment length of 450 bp). a The bias occurs around each integer copy number and is lower for CNRD ~ 1, but increases for CNRD ~ 2. The factor for normalisation is a linear function (eq. 1b) which serves to adjust the bias for different CNRD. b Distribution of absolute copy numbers called with ReadDepth after normalisationBack to article page