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Table 1 The clinical characteristics of enrolled patients

From: Leukocyte telomere length in patients with transfusion-dependent thalassemia

Clinical characteristicsN = 65 (%)
Female37 (54.4)
Median age (year) (range)27.0 (18–57)
Baseline pre-transfusion Hb level (g/dL) (range)7.1 (4.8–10.1)
Red blood cell transfusion (unit per month) (range)1.67 (0.33–2)
Type of thalassemia
 Beta-thalassemia/Hb E disease39 (57.4)
 Homozygous beta-thalassemia24 (35.3)
 Hb H with Constant Spring disease2 (2.9)
Splenectomy46 (67.6)
Median serum ferritin level (mcg/dL) (range)1499 (272–7371)
Median reticulocyte count (%) (range)5.2 (0.27–31.2)
Median absolute reticulocyte count (×106/mm3) (range)155.4 (11–1370)
Median Cardiac T2* (ms)38.3
  > 2054 (79.4)
 10–202 (2.9)
  < 105 (7.4)
Median LIC (mg/g of dry weight)14.8 (1.3–27.0)
  < 77 (11.7)
 7–1523 (38.3)
  > 1530 (50.0)
Liver enzymes (U/L)
 Median AST (range)39.48 (16–136)
 Median ALT (range)34.98 (4–175)
 Mean NTBI (micromol/L) (range)6.94 (2.22–10.00)
  1. AST Aspartate transaminase; ALT Alanine transaminase; LIC liver iron concentration;
  2. NTBI Non-transferrin bound iron