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Table 1 The clinical characteristics of enrolled patients

From: Leukocyte telomere length in patients with transfusion-dependent thalassemia

Clinical characteristics

N = 65 (%)

Female

37 (54.4)

Median age (year) (range)

27.0 (18–57)

Baseline pre-transfusion Hb level (g/dL) (range)

7.1 (4.8–10.1)

Red blood cell transfusion (unit per month) (range)

1.67 (0.33–2)

Type of thalassemia

 Beta-thalassemia/Hb E disease

39 (57.4)

 Homozygous beta-thalassemia

24 (35.3)

 Hb H with Constant Spring disease

2 (2.9)

Splenectomy

46 (67.6)

Median serum ferritin level (mcg/dL) (range)

1499 (272–7371)

Median reticulocyte count (%) (range)

5.2 (0.27–31.2)

Median absolute reticulocyte count (×106/mm3) (range)

155.4 (11–1370)

Median Cardiac T2* (ms)

38.3

  > 20

54 (79.4)

 10–20

2 (2.9)

  < 10

5 (7.4)

Median LIC (mg/g of dry weight)

14.8 (1.3–27.0)

  < 7

7 (11.7)

 7–15

23 (38.3)

  > 15

30 (50.0)

Liver enzymes (U/L)

 Median AST (range)

39.48 (16–136)

 Median ALT (range)

34.98 (4–175)

 Mean NTBI (micromol/L) (range)

6.94 (2.22–10.00)

  1. AST Aspartate transaminase; ALT Alanine transaminase; LIC liver iron concentration;
  2. NTBI Non-transferrin bound iron