Fig. 2
From: Detection of leukemia gene fusions by targeted RNA-sequencing in routine diagnostics
Illustration of artifacts detected by the Archer™ FusionPlex™ Heme Panel version 1 and the Archer™ Analysis Software. a. The retrieved sequence read contains sequences that match to a non-coding RNA, MAN1B1-DT, and the TAL1 gene. The last part of the sequence contains part of exon 3 of the TAL1 gene and the noncoding MAN1B1-DT RNA-transcript with a sequence overlap of 15 bp. b. Possible transcription readthrough event between exon 1 of the ATP5MG gene and exon 2 of the KMT2A gene located downstream of the ATP5MG gene