Fig. 2

GO term enrichment analysis for DEGs revealed several biological processes associated with PAH. ClueGo network analysis was performed for all differentially expressed genes(a), up-regulated DEGs (b) and down-regulated DEGs (c). Enrichment for GO groups was conducted using the ClueGO plug-in. Nodes were colored according to grouping of related functions by statistically significant association of related GO terms. In each group, only the most significant term was labeled, and the node size corresponded to the significance of each GO term