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Table 3 Top 10 upstream regulators involved in DE lncRNAs in WNT subgroup

From: Long non-coding RNA profiling of pediatric Medulloblastoma

Upstream Regulator

Molecule Type

P-val of overlap

Target molecules in dataset

MAX

transcription regulator

5.53E-03

DLEU1,DLEU2

miR-150-5p (and other miRNAs w/seed CUCCCAA)

mature microRNA

5.54E-03

MIAT

miR-133a-3p (and other miRNAs w/seed UUGGUCC)

mature microRNA

7.38E-03

MALAT1

mir-133

microRNA

9.22E-03

MALAT1

FOLR1

transporter

1.31E-02

GAS5,PVT1

E2f

group

1.37E-02

DLEU1,DLEU2

ATF5

transcription regulator

1.47E-02

GAS5

NCAM1

other

1.84E-02

MALAT1

mir-150

microRNA

2.56E-02

MIAT

GAS2L3

other

2.92E-02

PVT1