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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Comparative analysis of somatic variant calling on matched FF and FFPE WGS samples

Fig. 4

Evaluating the overlap between clonal variants from FF and FFPE samples of UZ001. By first defining the clonal and subclonal variants (see main text), it is possible to calculate the overlap between clonal variants only. Compared to Fig. 1, only variants using the at least two approach are shown, which are known to lie in diploid regions in both FF and FFPE and can be considered clonal. Overlap: red (green) refers to variants in the FFPE (FF) sample also found in the FF (FFPE) sample. Clearly, these additional filtering steps lead to an appreciable improvement in overlap between the FF and the FFPE sample

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