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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gene expression

Fig. 3

KEGG pathway enrichment shows differences between ER+ and ER- HER2+ cell lines. The KEGG pathway enrichment analysis for the genes containing the H3K4me3 (K4) or H3K27me3 (K27) histone modifications for the ER- (a) and ER+ (b) HER2+ cell lines used in this study. The number in brackets at the bottom represents the number of individual genes with peaks located within −2000 to + 1000 bp from a TSS, the size of the dot represents the gene ratio of unique genes found to contain a peak within that pathway, the pathways that are enriched are labeled on the left-hand side, and the colour of the dot represents the range of adjusted p-values (p-value < 0.05)

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BMC Medical Genomics

ISSN: 1755-8794

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