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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Next-generation sequencing analysis of endometrial screening liquid-based cytology specimens: a comparative study to tissue specimens

Fig. 3

Representative H&E sections and IHC for MMR protein expression. a Scanning view of endometrioid carcinoma G2 (H&E, original magnification: 40×). b Higher power view of the endometrioid carcinoma G2 arranged in solid and glandular patterns (H&E, original magnification: 200×). c Absent expression of MLH1 in both the glandular and solid components (IHC, original magnification 200×). d Absent expression of PMS2 (IHC, original magnification 200×). e MSH2 expression was noted in both components (IHC, original magnification 200×). f MSH6 expression was also observed in the glandular and solid parts (IHC, original magnification 200×). Note the expression of these four proteins in stromal lymphocytes as an internal control

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