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Table 2 Pathological and DNA sample information for NGS analysis

From: Next-generation sequencing analysis of endometrial screening liquid-based cytology specimens: a comparative study to tissue specimens

Case no. Sample no. Samples Pathological diagnosis Storage time DNA yield (ng/μL) QC score Input DNA (ng) Tumor fraction in FFPE (%) Tumor cell count and tumor cell ratio in LBC Insufficient VAF call
Tumor cells (T) Non-tumor cells (N) Tumor cell ratio (T/N+T)%
1 1 SR(Ut) EC G1 1 m 1.655 0.012 200 30     
2 2 SR(Ut) EC G1 2 m 5.510 0.003 100 80     
3 3 SR(Ut) EC G2 1 m 2.980 0.008 100 60     
4 4 SR(Ut) EC G1 1 m 1.521 0.016 200 50     
5 5 SR(Ut) EC G1 3 m 4.033 0.010 119 80     
6 6 SR(Ut) EC G1 3 m 6.636 0.003 72 30     
  7 SR(Ut) EC G2 3 m 6.071 0.004 79 60     
7 8 SR(Ut) EC G1 + Sq 1 m 5.912 0.003 200 70     
8 9 SR(Ut) Mixed EC/SC 2 m 3.487 0.010 138 50     
  10 SR(Om) Mixed EC/SC 2 m 4.897 0.007 98 30     
9 11 Bx SC 3 m 6.425 0.004 75 80     
  12 SR(Ut) CCC 3 m 1.930 0.015 168 90     
  13 End LBC AC 3 m 28.879 0.000 20   6661 10,059 39.8  
10 14 SR(Ut) DC 3 m 3.337 0.007 144 70     
  15 SR(Ut) EC G1 3 m 5.743 0.004 84 70     
11 16 SR(Ut) AC 1 m 2.327 0.011 168 60     
  17 SR(Ut) DC 1 m 0.939 0.016 168 50     
  18 SR(Ov) EC G3 1 m 1.778 0.012 168 40     
12 19 Bx AC 1 m 2.264 0.010 168 60     
  20 SR(Ut) EC G2 1 m 3.025 0.006 168 70     
  21 End LBC Malig 2 m 21.861 0.002 22   19,588 4087 82.7  
13 22 SR(Ut) EC G1 1 m 2.338 0.010 168 50     
14 23 Bx EC G1 1 m 5.664 0.001 85 70     
  24 End LBC AGC 2 m 23.839 −0.003 10   1450 136 91.4  
15 25 SR(Ut) DC 1 m 6.249 0.008 77 90     
  26 SR(Ut) AC 1 m 5.830 0.010 85 90     
16 27 Bx AC 1 m 5.029 0.010 95 80     
  28 SR(Ut) Serous 1 m 0.872 0.017 168 40     
  29 End LBC AC 2 m 14.257 0.005 31   22,261 3928 85.0  
17 30 SR(Ut) AH 1 m 3.443 0.007 140 70     
  31 SR(Ut) EC G1 1 m 4.137 0.006 116 60     
18 32 Bx EC G1 1 m 3.794 0.009 127 90     
  33 SR(Ut) EC G1 1 m 3.025 0.012 168 80     
  34 End LBC EC 2 m 3.392 0.008 11   8043 20,911 27.8 *
19 35 SR(Ut) EC G1 + Sq 2 m 4.585 0.004 105 30     
  36 End LBC EC 4 m 16.984 0.000 26   7739 9261 45.5  
20 37 Bx EC G2 3y 0.492 0.022 168 60     
21 38 Bx EC G1 3 m 2.612 0.012 168 90     
  39 SR(Ut) EC G1 1 m 1.321 0.025 154 90     
  40 End LBC EC 3 m 16.114 0.005 36   16,855 10,739 61.1  
22 41 Bx EC G3 2y 1.024 0.022 168 40     
  42 End LBC AGC 1 m 16.208 0.004 30   14,816 1019 93.6  
23 43 Bx AC 2 m 3.479 0.010 138 90     
  44 SR(Ut) EC G2 2w 2.443 0.012 168 90     
  45 End LBC EC 2 m 8.576 0.004 54   45,220 2537 94.7  
24 46 Bx EC 4 m 2.443 0.009 168 80     
  47 SR(Ut) EC G1 2 m 5.058 0.005 95 80     
  48 SR(Ov) EC G1 2 m 1.694 0.011 168 70     
  49 End LBC AC 4 m 24.088 −0.001 31   21,930 6661 76.7  
  1. SRsurgical resection,BxEndometrial biopsy,LBCliquid-based cytology,EndEndometrial,UtUterus,OmOmentumOvOvary,ECEndometrioid carcinoma,SCSerous carcinoma,CCCClear cell carcinoma,ACAdenocarcinoma,SqSquamous differentiation,DCDedifferentiated carcinoma,MaligMalignant cell,AGCAtypical glandular cell,AHAtypical hyperplasia,w, week,mmonthy, year