Fig. 1
Validated Associations with Obstructive Sleep Apnea Diagnosis in European Americans. Plotted are the estimates of the additive effects (beta) of the minor allele at each candidate SNP associated with a validated definition of OSA obtained from the EHR, along with the corresponding -log10p-value. For each SNP, the rsID, chromosome and hg38 base pair location are provided. Results from analyses conducted in the Geisinger European American (EA) dataset are plotted in blue, VUMC European Americans in red, and meta-analyses of results from tests conducted in both European American datasets in green. For p-values, up arrows denote increased risk for OSA diagnosis given the minor allele at this SNP and down arrows denote reduced risk. Red line denotes unadjusted significance threshold (p < 5.0 × 10− 2)