Fig. 7
From: Analysis of exosomal circRNAs upon irradiation in pancreatic cancer cell repopulation
Hsa_circ_0002130-hsa_miR_4482-3p-NBN interaction axis. a The circRNA-miRNA-mRNA interaction network was predicted using online bioinformatics programs (Circinteractome, Circbank, TargetScan, and miRBase). The red circle indicated the up-regulated circRNAs, the green indicated the down-regulated ones, the arrow and the hexagon indicated miRNAs and target genes respectively. b The predicted binding sites between hsa_circ_0002130 and hsa_miR_4482-3p were exhibited. c The expression of hsa_circ_0002130 in PANC-1 cells (Left) and PDX tumors (Right) were examined respectively by qRT-PCR. d The expression of NBN was determined by qRT-PCR in samples of sequencing, PANC-1 and SW1990. *p-value < 0.05 and data indicated the mean ± SD. e The survival data from TCGA (Log rank p-value = 0.0234)