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Table 1 Analysis of aneuploidies in quality control cells to establish internal quality controls (IQCs) for molecular genetic diagnosis (\( \overline{\mathrm{X}\ } \) /SD/ \( \overline{\mathrm{X}\ } \) ±1SD/2SD/3SD)

From: A novel use for Levey-Jennings charts in prenatal molecular diagnosis

Group Aneuploidy Test (time) Theoretical Ratio (%) \( \overline{\mathbf{X}\ } \)(n = 20) SD \( \overline{\mathbf{X}\ } \)±1SD \( \overline{\mathbf{X}} \)±2SD \( \overline{\mathbf{X}} \)±3SD
A trisomy 13 20 10 10.2 1.7 10.2 ± 1.7 10.2 ± 3.4 10.2 ± 5.1
trisomy 21 20 90 90.3 2.3 90.3 ± 2.3 90.3 ± 4.6 90.3 ± 6.9
B trisomy 13 20 30 30.4 2.4 30.4 ± 2.4 30.4 ± 4.8 30.4 ± 7.2
trisomy 21 20 70 69.8 2.6 69.8 ± 2.6 69.8 ± 5.2 69.8 ± 7.8
C trisomy 13 20 70 70.3 2.4 70.3 ± 2.4 70.3 ± 4.8 70.3 ± 7.2
trisomy 21 20 30 30.8 2.1 30.8 ± 2.1 30.8 ± 4.2 30.8 ± 6.3
D trisomy 13 20 90 90.1 2.4 90.1 ± 2.4 90.1 ± 4.8 90.1 ± 7.2
trisomy 21 20 10 10.1 1.4 10.1 ± 1.4 10.1 ± 2.8 10.1 ± 4.2
E trisomy 18 20 10 10.3 1.9 10.3 ± 1.9 10.3 ± 3.8 10.3 ± 5.7
47,XXY 20 90 90.6 2.4 90.6 ± 2.4 90.6 ± 4.8 90.6 ± 7.2
F trisomy 18 20 30 30.0 2.6 30.0 ± 2.6 30.0 ± 5.2 30.0 ± 7.8
47,XXY 20 70 69.8 2.5 69.8 ± 2.5 69.8 ± 5.0 69.8 ± 7.5
G trisomy 18 20 70 70.1 2.4 70.1 ± 2.4 70.1 ± 4.8 70.1 ± 7.2
47,XXY 20 30 29.9 2.6 29.9 ± 2.6 29.9 ± 5.2 29.9 ± 7.8
H trisomy 18 20 90 90.6 2.6 90.6 ± 2.6 90.6 ± 5.2 90.6 ± 7.8
47,XXY 20 10 10.1 1.3 10.1 ± 1.3 10.1 ± 2.6 10.1 ± 3.9