Table 1 Analysis of aneuploidies in quality control cells to establish internal quality controls (IQCs) for molecular genetic diagnosis (\( \overline{\mathrm{X}\ } \) /SD/ \( \overline{\mathrm{X}\ } \) ±1SD/2SD/3SD)
From: A novel use for Levey-Jennings charts in prenatal molecular diagnosis
Group | Aneuploidy | Test (time) | Theoretical Ratio (%) | \( \overline{\mathbf{X}\ } \)(n = 20) | SD | \( \overline{\mathbf{X}\ } \)±1SD | \( \overline{\mathbf{X}} \)±2SD | \( \overline{\mathbf{X}} \)±3SD |
|---|---|---|---|---|---|---|---|---|
A | trisomy 13 | 20 | 10 | 10.2 | 1.7 | 10.2 ± 1.7 | 10.2 ± 3.4 | 10.2 ± 5.1 |
trisomy 21 | 20 | 90 | 90.3 | 2.3 | 90.3 ± 2.3 | 90.3 ± 4.6 | 90.3 ± 6.9 | |
B | trisomy 13 | 20 | 30 | 30.4 | 2.4 | 30.4 ± 2.4 | 30.4 ± 4.8 | 30.4 ± 7.2 |
trisomy 21 | 20 | 70 | 69.8 | 2.6 | 69.8 ± 2.6 | 69.8 ± 5.2 | 69.8 ± 7.8 | |
C | trisomy 13 | 20 | 70 | 70.3 | 2.4 | 70.3 ± 2.4 | 70.3 ± 4.8 | 70.3 ± 7.2 |
trisomy 21 | 20 | 30 | 30.8 | 2.1 | 30.8 ± 2.1 | 30.8 ± 4.2 | 30.8 ± 6.3 | |
D | trisomy 13 | 20 | 90 | 90.1 | 2.4 | 90.1 ± 2.4 | 90.1 ± 4.8 | 90.1 ± 7.2 |
trisomy 21 | 20 | 10 | 10.1 | 1.4 | 10.1 ± 1.4 | 10.1 ± 2.8 | 10.1 ± 4.2 | |
E | trisomy 18 | 20 | 10 | 10.3 | 1.9 | 10.3 ± 1.9 | 10.3 ± 3.8 | 10.3 ± 5.7 |
47,XXY | 20 | 90 | 90.6 | 2.4 | 90.6 ± 2.4 | 90.6 ± 4.8 | 90.6 ± 7.2 | |
F | trisomy 18 | 20 | 30 | 30.0 | 2.6 | 30.0 ± 2.6 | 30.0 ± 5.2 | 30.0 ± 7.8 |
47,XXY | 20 | 70 | 69.8 | 2.5 | 69.8 ± 2.5 | 69.8 ± 5.0 | 69.8 ± 7.5 | |
G | trisomy 18 | 20 | 70 | 70.1 | 2.4 | 70.1 ± 2.4 | 70.1 ± 4.8 | 70.1 ± 7.2 |
47,XXY | 20 | 30 | 29.9 | 2.6 | 29.9 ± 2.6 | 29.9 ± 5.2 | 29.9 ± 7.8 | |
H | trisomy 18 | 20 | 90 | 90.6 | 2.6 | 90.6 ± 2.6 | 90.6 ± 5.2 | 90.6 ± 7.8 |
47,XXY | 20 | 10 | 10.1 | 1.3 | 10.1 ± 1.3 | 10.1 ± 2.6 | 10.1 ± 3.9 |