TY - JOUR AU - Wei, Rong AU - Wang, Ziyue AU - Zhang, Yaping AU - Wang, Bin AU - Shen, Ningning AU - E, Li AU - Li, Xin AU - Shang, Lifang AU - Shang, Yangwei AU - Yan, Wenpeng AU - Zhang, Xiaoqin AU - Ma, Wenxia AU - Wang, Chen PY - 2020 DA - 2020/08/14 TI - Bioinformatic analysis revealing mitotic spindle assembly regulated NDC80 and MAD2L1 as prognostic biomarkers in non-small cell lung cancer development JO - BMC Medical Genomics SP - 112 VL - 13 IS - 1 AB - Lung cancer has been the leading cause of tumor related death, and 80% ~ 85% of it is non-small cell lung cancer (NSCLC). Even with the rising molecular targeted therapies, for example EGFR, ROS1 and ALK, the treatment is still challenging. The study is to identify credible responsible genes during the development of NSCLC using bioinformatic analysis, developing new prognostic biomarkers and potential gene targets to the disease. SN - 1755-8794 UR - https://doi.org/10.1186/s12920-020-00762-5 DO - 10.1186/s12920-020-00762-5 ID - Wei2020 ER -