Skip to main content
Fig. 4 | BMC Medical Genomics

Fig. 4

From: Integrative genomics analysis of various omics data and networks identify risk genes and variants vulnerable to childhood-onset asthma

Fig. 4

Consistent evidence of childhood-onset asthma-relevant genes based on independent datasets and techniques. a Venn diagram of three identified childhood-onset asthma-relevant gene sets: Dataset #1 based on MAGMA analysis of GWAS summary data (P value of each gene with Bonferroni correction), Dataset #2 based on Sherlock integrative analysis of integrating GWAS and Zeller et al. eQTL data (P value of each gene with FDR correction), and Dataset #3 based on Sherlock analysis of integrating GWAS and Dixon et al. eQTL data (raw P value of each gene was applied). b Computer-based permutation analysis of 105 times for the comparison of genes with adjusted P-values from Dataset #2 with that from MAGMA analysis. c Computer-based permutation analysis of 105 times for the comparison of genes with adjusted P-values from Dataset #2 with that from Dataset #3

Back to article page