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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Expression correlation attenuates within and between key signaling pathways in chronic kidney disease

Fig. 5

Disruption of pathway crosstalk in CKD progression. a pathway crosstalks present in early CKD were disrupted in late CKD. Node size and edge width are proportional to the statistical significance of correlation loss (extremity of p value). b attenuated cross-pathway gene correlation links incident to the affected pathways. For clarity, only links pertaining to Differentially Coexpressed Genes or hub genes were shown. Node size, vertex degree. Node color, pathway membership. Red text, pathway hub genes. Asterisk (*), differentially expressed genes (FDR < 0.3)

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BMC Medical Genomics

ISSN: 1755-8794

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