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Table 3 Gene pair identification of novel tumorigenic genes to distinguish between breast cancer and control tissue. Genes represent those that were present in at least 10% of the top 100 pairs in at least one of the feature selection methods. Feature selection columns denote the number of occurrences in the top 100 gene pairs

From: Considerations for feature selection using gene pairs and applications in large-scale dataset integration, novel oncogene discovery, and interpretable cancer screening

Gene Symbol Gene Name TSP AM AA FM FA Function Location
BSDC1 BSD domain containing 1 29 30 63 47 33 Unknown 1p35.1
C3orf14 Chromosome 3 open reading frame 14 0 4 11 0 0 Unknown 3p14.2
CDR2L Cerebral degeneration related protein 2 like 11 0 1 11 16 Antigen for onconeural antibody (Yo) 17q25.1
LRRC42 Leucine rich repeat containing 42 41 3 9 29 22 Nuclear protein 1p.32.3
NRG2 Neuregulin 2 0 14 6 8 8 Growth factor 5q31.2
PLEKHA6 Pleckstrin homology domain containing A6 10 1 5 5 13 Intracellular signaling 1q32.1
SCARF1 Scavenger receptor class F1 0 26 5 1 3 LDL receptor 17p13.3