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Table 3 Gene pair identification of novel tumorigenic genes to distinguish between breast cancer and control tissue. Genes represent those that were present in at least 10% of the top 100 pairs in at least one of the feature selection methods. Feature selection columns denote the number of occurrences in the top 100 gene pairs

From: Considerations for feature selection using gene pairs and applications in large-scale dataset integration, novel oncogene discovery, and interpretable cancer screening

Gene Symbol

Gene Name

TSP

AM

AA

FM

FA

Function

Location

BSDC1

BSD domain containing 1

29

30

63

47

33

Unknown

1p35.1

C3orf14

Chromosome 3 open reading frame 14

0

4

11

0

0

Unknown

3p14.2

CDR2L

Cerebral degeneration related protein 2 like

11

0

1

11

16

Antigen for onconeural antibody (Yo)

17q25.1

LRRC42

Leucine rich repeat containing 42

41

3

9

29

22

Nuclear protein

1p.32.3

NRG2

Neuregulin 2

0

14

6

8

8

Growth factor

5q31.2

PLEKHA6

Pleckstrin homology domain containing A6

10

1

5

5

13

Intracellular signaling

1q32.1

SCARF1

Scavenger receptor class F1

0

26

5

1

3

LDL receptor

17p13.3