Table 4 Top genes for classification of tumors based on ER status. Genes represent those that were present in at least 10% of the top 100 pairs in at least one of the feature selection methods. Feature selection columns denote the number of occurrences in the top 100 gene pairs
Gene Symbol | Gene Name | TSP | AM | AA | FM | FA | Function | Location |
|---|---|---|---|---|---|---|---|---|
ATP6AP2 | ATPase H+ transporting accessory protein 2 | 0 | 39 | 3 | 1 | 0 | Vacuolar-ATPase, pH control | Xp11.4 |
CSNK1A1 | Casein kinase 1 alpha 1 | 0 | 13 | 3 | 0 | 0 | Tumor suppressor, Wnt/β-catenin signaling | 5q32 |
ESR1 | Estrogen receptor 1 | 100 | 0 | 45 | 0 | 99 | Estrogen signaling | 6q25.1–2 |
INAVA | Innate immunity activator | 1 | 1 | 17 | 0 | 1 | Adherens junctions | 1q32.1 |
SOX11 | SRY-box 11 | 0 | 0 | 12 | 0 | 2 | Transcription factor, cell fate | 2p25.2 |
TPM3 | Tropomyosin 3 | 0 | 11 | 2 | 0 | 0 | Stabilization of actin filaments | 1q21.3 |
U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 1 | 34 | 22 | 93 | 1 | Splicing | 21q22.3 |