Fig. 7

The flowchart of MDAPCOM: a Obtain six kinds of data from online databases. b Merge these data to build a global heterogeneous network c Utilize RWR algorithm to get the diffusion feature. d Apply SVD to reduce dimension of the diffusion feature. e Use HeteSim measure to obtain HeteSim feature. f Integrate reduced diffusion feature and HeteSim feature and then apply XGBoost algorithm to train the model using the combined feature