Fig. 1

Comparative analysis of cold acclimation and exercise training on the human skeletal muscle transcriptome. a Volcano plot in which 2log(fold-change) is plotted against −10log-(P-value) for comparison pre-cold acclimation vs post-cold acclimation (left panel), and for the comparison pre-exercise training vs post-exercise training. b Principle component analysis of transcriptomics data from human skeletal muscle. The arrows indicate the change from pre-cold acclimation (base of red arrow) to post-cold acclimation (tip of red arrow) and from pre-exercise training (base of black arrow) to post-exercise training (tip of black arrow)