Table 3 Subgroup analysis of AHCY and CBS methylation levels by gender or age
Factors | AHCYâ–² (%) | AHCYâ–³ (%) | P value | CBSâ–² (%) | CBSâ–³ (%) | P value |
|---|---|---|---|---|---|---|
Gender | ||||||
 Male (n = 224) | 0.14 (0.05,0.30) | 0.26 (0.03,0.67) | 0.045 | 64.33 (47.72,85.66) | 105 (73.23,128.85) | 2.667E-08* |
 Female (n = 80) | 0.20 (0.11,0.35) | 0.24 (0.00,0.86) | 0.902 | 78.05 (51.81,107.90) | 102.8 (86.11,149.90) | 0.003* |
Age (years) | ||||||
  ≤ 44 (n = 25) | 0.20 ± 0.15 | 0.95 ± 1.17 | 0.06 | 69.97 ± 13.61 | 114.71 ± 59.62 | 0.015 |
 45 ~ 59 (n = 131) | 0.14 (0.04,0.31) | 0.03 (0,0.31) | 0.016 | 56.04 (48.07,76.23) | 91.71 (68.28,118.58) | 6.744E-06* |
  ≥ 60 (n = 148) | 0.18 (0.08,0.31) | 0.37 (0.14,1.29) | 4.05E-04 | 81.6 (49.37,127.45) | 119.35 (87.71,167.90) | 2.644E-04* |