Table 1 GO-BP terms related to neovascularization shared by GO1 and GO2
From: Comprehensive analysis of angiogenesis-related genes and pathways in early diabetic retinopathy
GO-BP terms | Genes in GO1 | Genes in GO2 |
|---|---|---|
positive regulation of smooth muscle cell proliferation | NAMPT, TNF, PDGFB, PTGS2, EDN1, PPARGC1A | PRKCA, NAMPT, TNF, PDGFB, PTGS2, AIF1, EDN1, AGER, PPARGC1A, HIF1A, VEGFA, THBS1, ALOX12 |
positive regulation of MAP kinase activity | EDN3, TNF, PDGFB, PDGFA, EDN1, VEGFA, TGFB1 | EDN3, TNF, PDGFB, PDGFA, VEGFA, EDN1, TPD52L1, FGF1, TGFB1 |
positive regulation of cell proliferation | VIP, NAMPT, EDN3, NTF3, PDGFB, PGF, PDGFA, EDN1, HGF, GDNF, TGFB1, CXCL10, CNTF, VEGFA | EDN3, TNF, PTGS2, PDGFB, PGF, PDGFA, EDN2, EDN1, FGF10, GDNF, GHRHR, TGFB1, CXCL10, ALDH3A1, EDNRA, GADD45GIP1, THBS1, FGF1, TRAF5, APLN, NTF3, HGF, PLAC8, OSM, PRAMEF12, CNTF, HIF1A, VEGFA, ALOX12, NGF |
positive regulation of cell migration | PRKCA, NTF3, PDGFB, PDGFA, SEMA3E, EDN1, VEGFA, HGF, TGFB1 | PRKCA, PDGFB, NTF3, PDGFA, AIF1, EDN1, HGF, AQP1, MMP2, AGER, TGFB1, CXCL10, VEGFA, SEMA3E, SEMA3C, COL1A1, THBS1, FGF1, MYOC, ALOX12 |
positive regulation of blood vessel endothelial cell migration | PRKCA, PDGFB, VEGFA, HSPB1, ANGPT1, TGFB1 | PRKCA, PDGFB, VEGFA, HSPB1, ANGPT1, THBS1, TGFB1 |
positive regulation of angiogenesis | PRKCA, UTS2, PGF, CXCL8, HGF, AQP1, PTGIS, HIF1A, VEGFA, HSPB1, ANGPT2, ANGPTL4 | PRKCA, UTS2, PGF, MMP9, C6, HGF, AQP1, TNFRSF1A, HIF1A, PTGIS, VEGFA, HSPB1, UTS2R, FGF1, THBS1, ANGPT2, ALOX12 |
angiogenesis | PRKCA, HIF1A, CCL2, PTGS2, PDGFA, PGF, VEGFA, CXCL8, ANGPT1, ANGPT2, ANGPTL4 | PRKCA, COL4A1, CCL2, PTGS2, PDGFA, PGF, FGF10, MMP2, HOXB3, TAL1, HIF1A, DLL4, FAP, VEGFA, SEMA3E, ANGPT1, COL8A1, FGF1, COL8A2, ANGPT2, ANGPTL4 |