Fig. 4
From: TOP2A and CENPF are synergistic master regulators activated in cervical cancer
Synergistic effect of TOP2A and CENPF. a Regulon enrichment plot of regulons of TOP2A (left), CENPF (middle) or common regulons (right). For each dataset, all genes were sorted based on the DE signature from most down-regulated to most up-regulated. The position of regulons in the sorted gene list was shown as a vertical blue (negative regulons) or red (positive regulons) bar. b Network view of TOP2A, CENPF and their regulons. Node color represents the average DE signature in the 10 datasets. Edge color represent the MOR of a MR and a regulon. c DAVID function annotation of the common regulons of TOP2A and CENPF