Fig. 1

Representative MS results showing paired tumor and adjacent normal tissues from frozen and FFPE tissues. Shown in (a), (b), and (c) are three different mutations in the TP53, APC and KRAS genes from three frozen tissues, (d), (e) and (f) show the mass spectra for three FFPE tissues. Mutant allele frequency can be estimated by comparing the peak signals for the mutant and wild type alleles. Wt: wild type, Mut: mutation