BMC Medical Genomics

Table 2 Percent change in power between ES-MDR and Surv-MDR

From: A new efficient method to detect genetic interactions for lung cancer GWAS

Heritability	0.01 (%)	0.02 (%)	0.05 (%)	0.10 (%)	0.20 (%)	0.30 (%)	0.40 (%)
n^a = 400
maf^a
0.2	0.0	− 16.7	− 30.0	9.1	13.6	− 2.5	− 0.3
0.4	− 66.7	0.0	− 15.8	7.7	0.0	− 0.4	5.2
n^a = 800
maf^a
0.2	100.0	16.7	15.8	16.4	− 4.0	− 6.0	− 3.9
0.4	38.5	4.8	9.7	3.8	1.0	1.1	− 0.1
n^a = 1600
maf^a
0.2	433.3	1.1	6.3	28.2	7.5	3.3	− 5.0
0.4	24.3	15.7	5.0	8.0	− 1.7	− 0.5	0.6

^an, sample size; maf, minor allele frequency;
^b% change calculator = ((ES-MDR − Surv-MDR)/Surv-MDR) × 100%

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ISSN: 1755-8794

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