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Table 3 Percent change in power between ES-MDR and Surv-MDR

From: A new efficient method to detect genetic interactions for lung cancer GWAS

Heritability 0.01 (%) 0.02 (%) 0.05 (%) 0.10 (%) 0.20 (%) 0.30 (%) 0.40 (%)
na = 400
mafa
0.2 25.0 10.0 − 34.7 − 1.2 20.6 7.0 4.2
0.4 − 80.0 − 10.5 − 4.6 11.3 9.0 1.4 4.6
na = 800
mafa
0.2 16.7 17.6 25.3 21.4 7.5 − 0.7 1.0
0.4 16.7 − 16.7 − 10.7 7.1 11.4 7.5 1.4
na = 1600
mafa
0.2 152.6 19.4 17.9 16.6 6.6 0.3 0.0
0.4 26.7 17.2 2.6 6.6 3.4 0.6 0.0
  1. an, sample size; maf, minor allele frequency;
  2. b% change calculator = (ES-MDR − Surv-MDR)/Surv-MDR × 100%