BMC Medical Genomics

Table 3 Percent change in power between ES-MDR and Surv-MDR

From: A new efficient method to detect genetic interactions for lung cancer GWAS

Heritability	0.01 (%)	0.02 (%)	0.05 (%)	0.10 (%)	0.20 (%)	0.30 (%)	0.40 (%)
n^a = 400
maf^a
0.2	25.0	10.0	− 34.7	− 1.2	20.6	7.0	4.2
0.4	− 80.0	− 10.5	− 4.6	11.3	9.0	1.4	4.6
n^a = 800
maf^a
0.2	16.7	17.6	25.3	21.4	7.5	− 0.7	1.0
0.4	16.7	− 16.7	− 10.7	7.1	11.4	7.5	1.4
n^a = 1600
maf^a
0.2	152.6	19.4	17.9	16.6	6.6	0.3	0.0
0.4	26.7	17.2	2.6	6.6	3.4	0.6	0.0

^an, sample size; maf, minor allele frequency;
^b% change calculator = (ES-MDR − Surv-MDR)/Surv-MDR × 100%

Back to article page

ISSN: 1755-8794

Contact us

Submission enquiries: bmcmedicalgenomics@biomedcentral.com
General enquiries: ORSupport@springernature.com