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Table 1 Cytogenetic profile of breast cancer patients and controls

From: In silico pathway analysis based on chromosomal instability in breast cancer patients

 

Patients

Controls

p-value

No. of subjects

150

150

 

Age (Mean ± SD)

50.2 ± 11.5

49.2 ± 14.6

0.51

Mean (%) aberrant metaphases

22.6 ± 12.3

12.5 ± 4.6

 < 0.0001

Mean (%) metaphases with structural aberrations

11.7 ± 10.8

4.5 ± 3.1

 < 0.0001

Mean (%) metaphases with numerical aberrations

9.5 ± 6.7

6.2 ± 3.5

 < 0.0001

Mean (%) metaphases with both structural and numerical aberrations

2.6 ± 2.0

2.6 ± 1.1

1.00

Mean(%) metaphases with acrocentric associations

27.6 ± 14.7

28.9 ± 14.6

0.32

  1. Significant p-value (< 0.05), calculated by t-test, are shown in bold