Fig. 6
From: Involvement of NEK2 and its interaction with NDC80 and CEP250 in hepatocellular carcinoma
The genetic alterations and methylation level of NEK2, NDC80 and CEP250 in HCC. a The genetic alterations of NEK2, NDC80 and CEP250 in HCC. The queried genes (NEK2, NDC80, CEP250) were altered in 111/366 (30%) of queried samples. The genetic alteration frequencies of NEK2, NDC80 and CEP250 were 19%, 7% and 14%, respectively. The detailed genetic alteration types included Amplification, Missense Mutation, Truncating Mutation and mRNA High. b The methylation level of NEK2, NDC80 and CEP250 in HCC. Red represents high methylation level, and blue represents low methylation level