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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE)

Fig. 1

Workflow of the WIDE study. Patients with (a suspicion) of stage IV cancer undergoing a tumour biopsy as part of the routine standard of care at NKI are eligible for inclusion in the WIDE study. In addition, a blood sample is drawn. Subsequently, both a fresh frozen tumour and a blood sample are shipped to HMF for WGS analysis, and a tumour sample will be assessed according to standard of care (SOC). Both the results from WGS and SOC are discussed in a dedicated molecular tumour board and reported for clinical decision making. Alongside, a cost-effectiveness comparison of WGS versus SOC diagnostics will be performed

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