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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Considering the APOE locus in Alzheimer’s disease polygenic scores in the Health and Retirement Study: a longitudinal panel study

Fig. 3

Distribution of Alzheimer’s disease polygenic score, by number of copies of APOE-ε4 in the Health and Retirement Study, n = 9871. AD: Alzheimer’s disease; pT: p-value threshold for SNP-outcome association from the Alzheimer’s disease meta-analysis for inclusion into the polygenic score. APOE region defined as chromosome 19 (45,384,477 to 45,432,606, build 37/hg 19). This represents the start position of TOMM40 (45,394,477) − 10 KB and the stop position of APOC1 (45,422,606) + 10 KB

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