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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Mutational profiling of micro-dissected pre-malignant lesions from archived specimens

Fig. 2

Benchmarking results for variant calling. a, b Count of total variants from whole exome sequencing, separated by false positives (red), false negatives (black) and true positives (grey), before (a) and after (b) PML specific filtering. c, d Exome variant calling precision for various library preparation strategies and amount of input DNA (x-axis) before (c) and after (d) PML specific filtering. e, f Fraction of the genome involved in a copy number alteration (CNA burden—y axis) for all exome (e) and cancer panel (f) library preparation strategies and DNA input amounts. All error bars represent standard deviation

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