Fig. 4.

GO enrichment for genes in the top 10 significant modules 12 spatiotemporal points. Gene ontology term enrichment (biological process) analysis for five mental disorders in 12 spatiotemporal points. The top three GO terms were listed on the right for each spatiotemporal point in the order of “black”, “red”, and “blue”. Green dash indicated –log10 (p-value) after Bonferroni correction of all BP terms (1658). Red dash indicated significant –log10 (p-value) after Bonferroni correction of all BP terms and across 12 spatiotemporal points for 5 mental disorders. a ADHD: attention deficit hyperactivity disorder; b ASD: autism spectrum disorder; c BIP: bipolar disorder; d MDD: major depressive disorder; e SCZ: schizophrenia; FC: frontal cortex region, SM: sensory motor region, SC: sub-cortical region, TP: temporal-parietal cortex region, ST1: stage 1 (prenatal), ST2: stage 2 (after birth to 11 years old), ST3: stage 3 (older than 13 years).