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Table 2. Summary of nominal significant disorder-associated co-expression modules (Zn > 1.96) and module genes

From: Characterization of genome-wide association study data reveals spatiotemporal heterogeneity of mental disorders

  # modules (# genes)
ADHD ASD BIP MDD SCZ
FC_ST1 46 (134) 50 (175) 47 (160) 61 (191) 58 (177)
FC_ST2 38 (141) 41 (142) 47 (137) 35 (138) 44 (145)
FC_ST3 42 (137) 50 (176) 45 (107) 51 (124) 41 (128)
SC_ST1 43 (131) 46 (145) 41 (114) 59 (166) 47 (158)
SC_ST2 27 (96) 52 (161) 39 (143) 38 (131) 47 (135)
SC_ST3 44 (143) 42 (126) 58 (177) 56 (177) 47 (145)
SM_ST1 54 (185) 64 (196) 53 (170) 59 (179) 55 (195)
SM_ST2 33 (113) 44 (147) 48 (162) 49 (144) 45 (154)
SM_ST3 46 (155) 48 (150) 49 (147) 35 (105) 49 (155)
TP_ST1 51 (155) 53 (151) 36 (121) 50 (147) 50 (152)
TP_ST2 34 (107) 45 (159) 44 (155) 34 (128) 45 (170)
TP_ST3 45 (128) 40 (140) 37 (136) 50 (146) 40 (139)
  1. In Bold: The largest amount of co-expression modules or unique genes for each disorder in the 12 spatiotemporal points
  2. ADHD attention deficit hyperactivity disorder, ASD autism spectrum disorder, BIP bipolar disorder, MDD major depressive disorder, SCZ schizophrenia, FC frontal cortex region, SM sensory motor region, SC sub-cortical region, TP temporal-parietal cortex region, ST1 stage 1 (prenatal), ST2 stage 2 (after birth to 11 years old), ST3 stage 3 (older than 13 years)