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Table 2. Summary of nominal significant disorder-associated co-expression modules (Zn > 1.96) and module genes

From: Characterization of genome-wide association study data reveals spatiotemporal heterogeneity of mental disorders

 

# modules (# genes)

ADHD

ASD

BIP

MDD

SCZ

FC_ST1

46 (134)

50 (175)

47 (160)

61 (191)

58 (177)

FC_ST2

38 (141)

41 (142)

47 (137)

35 (138)

44 (145)

FC_ST3

42 (137)

50 (176)

45 (107)

51 (124)

41 (128)

SC_ST1

43 (131)

46 (145)

41 (114)

59 (166)

47 (158)

SC_ST2

27 (96)

52 (161)

39 (143)

38 (131)

47 (135)

SC_ST3

44 (143)

42 (126)

58 (177)

56 (177)

47 (145)

SM_ST1

54 (185)

64 (196)

53 (170)

59 (179)

55 (195)

SM_ST2

33 (113)

44 (147)

48 (162)

49 (144)

45 (154)

SM_ST3

46 (155)

48 (150)

49 (147)

35 (105)

49 (155)

TP_ST1

51 (155)

53 (151)

36 (121)

50 (147)

50 (152)

TP_ST2

34 (107)

45 (159)

44 (155)

34 (128)

45 (170)

TP_ST3

45 (128)

40 (140)

37 (136)

50 (146)

40 (139)

  1. In Bold: The largest amount of co-expression modules or unique genes for each disorder in the 12 spatiotemporal points
  2. ADHD attention deficit hyperactivity disorder, ASD autism spectrum disorder, BIP bipolar disorder, MDD major depressive disorder, SCZ schizophrenia, FC frontal cortex region, SM sensory motor region, SC sub-cortical region, TP temporal-parietal cortex region, ST1 stage 1 (prenatal), ST2 stage 2 (after birth to 11 years old), ST3 stage 3 (older than 13 years)