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Table 4 Hub genes identified from the top 10 significant modules (see Additional file 5)

From: Characterization of genome-wide association study data reveals spatiotemporal heterogeneity of mental disorders

Spatiotemporal point ADHD ASD BIP MDD SCZ
FC_ST1 ATF2 MYC CAND1 E2F4 EP300
FC_ST2 STAT3 CUL3 CTNNB1 HTT CREBBP
FC_ST3 ATF2 ACTB APP E2F4 EP300
SC_ST1 ATF2 MDM2 RBL2 TAF1 EP300
SC_ST2 ATF2 CUL3 ATF2 ATF2 EP300
SC_ST3 ATF2 CTNNB1 RBL2 DHX9 APP
SM_ST1 CTNNB1 RBL2 CUL2 NXF1 ATF2
SM_ST2 ATF2 CUL3 CCT4 UBE2I MYC
SM_ST3 CTNNB1 CUL3 ATF2 ATF2 RBL2
TP_ST1 ATF2 ELAVL1 ATF2 XPO1 HIST1H4B
TP_ST2 BTRC CUL3 ATF2 JUN HIST1H4D
TP_ST3 ATF2 GRB2 CTNNB1 E2F4 GRB2
  1. ADHD attention deficit hyperactivity disorder, ASD autism spectrum disorder, BIP bipolar disorder, MDD major depressive disorder, SCZ schizophrenia, FC frontal cortex region, SM sensory motor region, SC sub-cortical region, TP temporal-parietal cortex region, ST1 stage 1 (prenatal), ST2 stage 2 (after birth to 11 years old), ST3 stage 3 (older than 13 years)