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Table 4 Hub genes identified from the top 10 significant modules (see Additional file 5)

From: Characterization of genome-wide association study data reveals spatiotemporal heterogeneity of mental disorders

Spatiotemporal point

ADHD

ASD

BIP

MDD

SCZ

FC_ST1

ATF2

MYC

CAND1

E2F4

EP300

FC_ST2

STAT3

CUL3

CTNNB1

HTT

CREBBP

FC_ST3

ATF2

ACTB

APP

E2F4

EP300

SC_ST1

ATF2

MDM2

RBL2

TAF1

EP300

SC_ST2

ATF2

CUL3

ATF2

ATF2

EP300

SC_ST3

ATF2

CTNNB1

RBL2

DHX9

APP

SM_ST1

CTNNB1

RBL2

CUL2

NXF1

ATF2

SM_ST2

ATF2

CUL3

CCT4

UBE2I

MYC

SM_ST3

CTNNB1

CUL3

ATF2

ATF2

RBL2

TP_ST1

ATF2

ELAVL1

ATF2

XPO1

HIST1H4B

TP_ST2

BTRC

CUL3

ATF2

JUN

HIST1H4D

TP_ST3

ATF2

GRB2

CTNNB1

E2F4

GRB2

  1. ADHD attention deficit hyperactivity disorder, ASD autism spectrum disorder, BIP bipolar disorder, MDD major depressive disorder, SCZ schizophrenia, FC frontal cortex region, SM sensory motor region, SC sub-cortical region, TP temporal-parietal cortex region, ST1 stage 1 (prenatal), ST2 stage 2 (after birth to 11 years old), ST3 stage 3 (older than 13 years)